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  <xsd:element name="LicenseAgreementMinimumPeriodForEquitableRoyaltyPayableInCaseOfReversionLicense" id="nrxp_LicenseAgreementMinimumPeriodForEquitableRoyaltyPayableInCaseOfReversionLicense" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="InitialCashPaymentToBeReceived" id="nrxp_InitialCashPaymentToBeReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="SecondMilestonePaymentsReceivable" id="nrxp_SecondMilestonePaymentsReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="MaximumBonusMilestonePaymentsReceivable" id="nrxp_MaximumBonusMilestonePaymentsReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="AlvogenLicensingAgreementTextBlock" id="nrxp_AlvogenLicensingAgreementTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="MeasurementInputFairValuePerShareMember" id="nrxp_MeasurementInputFairValuePerShareMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MeasurementInputMarketInterestRateMember" id="nrxp_MeasurementInputMarketInterestRateMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MeasurementInputEquityVolatilityMember" id="nrxp_MeasurementInputEquityVolatilityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MeasurementInputVolumeVolatilityMember" id="nrxp_MeasurementInputVolumeVolatilityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LicenseAgreementThresholdAggregateLiquidity" id="nrxp_LicenseAgreementThresholdAggregateLiquidity" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="RelatedPartyTransactionConsultingFeePayablePerMonth" id="nrxp_RelatedPartyTransactionConsultingFeePayablePerMonth" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="RelatedPartyTransactionsPerformanceBasedAnnualBonusMinimumTarget" id="nrxp_RelatedPartyTransactionsPerformanceBasedAnnualBonusMinimumTarget" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="NumberOfSharesRestrictionsRemovedOnNewDrugApplicationDate" id="nrxp_NumberOfSharesRestrictionsRemovedOnNewDrugApplicationDate" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="NumberOfSharesRestrictionsRemovedOnNewDrugApprovalDate" id="nrxp_NumberOfSharesRestrictionsRemovedOnNewDrugApprovalDate" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="AmendmentTwoMember" id="nrxp_AmendmentTwoMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DefaultTriggerEventsMember" id="nrxp_DefaultTriggerEventsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SeriesConvertiblePreferredStockMember" id="nrxp_SeriesConvertiblePreferredStockMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ModificationOfWarrantsPolicyTextBlock" id="nrxp_ModificationOfWarrantsPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PreferredStockPolicyPolicyTextBlock" id="nrxp_PreferredStockPolicyPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentOriginalIssueDiscount" id="nrxp_DebtInstrumentOriginalIssueDiscount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtInstrumentPrepaymentAmountPayableAsPercentageOfPrincipalInterestAndFeesOwed" id="nrxp_DebtInstrumentPrepaymentAmountPayableAsPercentageOfPrincipalInterestAndFeesOwed" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="DebtInstrumentMaximumOutstandingBalanceThatCanBeRedeemedByHolderPerMonth" id="nrxp_DebtInstrumentMaximumOutstandingBalanceThatCanBeRedeemedByHolderPerMonth" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DebtInstrumentRedemptionPercentageOfPremiumPayableOnAmountRedeemedIfRedeemedInCash" id="nrxp_DebtInstrumentRedemptionPercentageOfPremiumPayableOnAmountRedeemedIfRedeemedInCash" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="DebtInstrumentRedemptionConversionPriceAsPercentageOfAverageLowestDailyVolumeWeightedAveragePricesPerShare" id="nrxp_DebtInstrumentRedemptionConversionPriceAsPercentageOfAverageLowestDailyVolumeWeightedAveragePricesPerShare" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentRedemptionConversionPriceNumberOfLowestDailyVolumeWeightedAveragePricesPerShareConsidered" id="nrxp_DebtInstrumentRedemptionConversionPriceNumberOfLowestDailyVolumeWeightedAveragePricesPerShareConsidered" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentRedemptionConversionPriceNumberOfTradingDaysConsidered" id="nrxp_DebtInstrumentRedemptionConversionPriceNumberOfTradingDaysConsidered" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentRedemptionTriggerMinimumPercentageOfDailyDollarTradingVolumeOfCommonStockConsidered" id="nrxp_DebtInstrumentRedemptionTriggerMinimumPercentageOfDailyDollarTradingVolumeOfCommonStockConsidered" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentRedemptionTriggerNumberOfPreviousTradingDaysOverWhichMedianDailyDollarTradingVolumeIsConsidered" id="nrxp_DebtInstrumentRedemptionTriggerNumberOfPreviousTradingDaysOverWhichMedianDailyDollarTradingVolumeIsConsidered" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentRedemptionTriggerMinimumPercentageByWhichClosingTradePriceExceedsNasdaqMinimumPriceConsidered" id="nrxp_DebtInstrumentRedemptionTriggerMinimumPercentageByWhichClosingTradePriceExceedsNasdaqMinimumPriceConsidered" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentRedemptionTriggerNumberOfFollowingTradingDaysOverWhichClosingTradePriceIsConsidered" id="nrxp_DebtInstrumentRedemptionTriggerNumberOfFollowingTradingDaysOverWhichClosingTradePriceIsConsidered" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentMonthlyRedemptionAmount" id="nrxp_DebtInstrumentMonthlyRedemptionAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="MaximumPercentageOfCommonStockOutstanding" id="nrxp_MaximumPercentageOfCommonStockOutstanding" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="DebtInstrumentAmountAgreedToPayInCashToAmendRedemptionProvisions" id="nrxp_DebtInstrumentAmountAgreedToPayInCashToAmendRedemptionProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DebtInstrumentMaximumMonthlyRedemptionAmountPerMonth" id="nrxp_DebtInstrumentMaximumMonthlyRedemptionAmountPerMonth" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DebtInstrumentPeriodicPaymentInterestPaidInCash" id="nrxp_DebtInstrumentPeriodicPaymentInterestPaidInCash" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtInstrumentPeriodicPaymentInterestPaidFromIssuanceOfStock" id="nrxp_DebtInstrumentPeriodicPaymentInterestPaidFromIssuanceOfStock" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtInstrumentPeriodicPaymentPrincipalPaidInCash" id="nrxp_DebtInstrumentPeriodicPaymentPrincipalPaidInCash" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtInstrumentPeriodicPaymentPrincipalPaidFromIssuanceOfStock" id="nrxp_DebtInstrumentPeriodicPaymentPrincipalPaidFromIssuanceOfStock" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="NetLossAttributableToCommonStockholders" id="nrxp_NetLossAttributableToCommonStockholders" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="GoingConcernAbstract" id="nrxp_GoingConcernAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NonCancellableContracts" id="nrxp_NonCancellableContracts" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ConversionOfPreferredStockIntoCommonStockValue" id="nrxp_ConversionOfPreferredStockIntoCommonStockValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ConversionOfPreferredStockIntoCommonStockShares" id="nrxp_ConversionOfPreferredStockIntoCommonStockShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AtMarketOfferingMember" id="nrxp_AtMarketOfferingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfSharesToBeIssued" id="nrxp_NumberOfSharesToBeIssued" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ProceedsFromIssuanceOfCommonStockAndWarrantsNetOfIssuanceCosts" id="nrxp_ProceedsFromIssuanceOfCommonStockAndWarrantsNetOfIssuanceCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="WarrantsIssued" id="nrxp_WarrantsIssued" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CommonStockAndWarrantsIssuedValueNewIssues" id="nrxp_CommonStockAndWarrantsIssuedValueNewIssues" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CommonStockAndWarrantsIssuedSharesNewIssues" id="nrxp_CommonStockAndWarrantsIssuedSharesNewIssues" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="InitialCashPaymentToBeReceivedAcceleratedAmount" id="nrxp_InitialCashPaymentToBeReceivedAcceleratedAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="InitialCashPaymentToBeReceivedRemainingAmount" id="nrxp_InitialCashPaymentToBeReceivedRemainingAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="AmendmentThreeMember" id="nrxp_AmendmentThreeMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PaymentOfRedemptionPremium" id="nrxp_PaymentOfRedemptionPremium" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="MilestonePaymentsPayable" id="nrxp_MilestonePaymentsPayable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SarahHerzogMemorialHospitalLicenseAgreementMember" id="nrxp_SarahHerzogMemorialHospitalLicenseAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="EndOfPhaseIClinicalTrialsOfLicensedProductMember" id="nrxp_EndOfPhaseIClinicalTrialsOfLicensedProductMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="EndOfPhaseIiClinicalTrialsOfLicensedProductMember" id="nrxp_EndOfPhaseIiClinicalTrialsOfLicensedProductMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ScheduleOfMilestonePaymentRelatedToLicenseAgreementTableTextBlock" id="nrxp_ScheduleOfMilestonePaymentRelatedToLicenseAgreementTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="EndOfPhaseIiiClinicalTrialsOfLicensedProductMember" id="nrxp_EndOfPhaseIiiClinicalTrialsOfLicensedProductMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FirstCommercialSaleOfLicensedProductInUsMember" id="nrxp_FirstCommercialSaleOfLicensedProductInUsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FirstCommercialSaleOfLicensedProductInEuropeMember" id="nrxp_FirstCommercialSaleOfLicensedProductInEuropeMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AnnualRevenuesReach100000000Member" id="nrxp_AnnualRevenuesReach100000000Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MilestonePaymentsAnnualRevenuesReach" id="nrxp_MilestonePaymentsAnnualRevenuesReach" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PercentageOfCertainCircumstances" id="nrxp_PercentageOfCertainCircumstances" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PercentageOfRevenueFromSaleOfProductNotCoveredByValidClaim" id="nrxp_PercentageOfRevenueFromSaleOfProductNotCoveredByValidClaim" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PercentageOfRevenueFromSaleOfProductCoveredByValidClaim" id="nrxp_PercentageOfRevenueFromSaleOfProductCoveredByValidClaim" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PercentageOfPaymentReceivedFromSubLicenseInSale" id="nrxp_PercentageOfPaymentReceivedFromSubLicenseInSale" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PaymentsForFixedAnnualMaintenanceFee" id="nrxp_PaymentsForFixedAnnualMaintenanceFee" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PaymentsForFixedAnnualMaintenanceFeeThereafter" id="nrxp_PaymentsForFixedAnnualMaintenanceFeeThereafter" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ApkarianTechnologiesExclusiveLicenseAgreementMember" id="nrxp_ApkarianTechnologiesExclusiveLicenseAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WorthOfExpensesRelatingToLicenseOfPatent" id="nrxp_WorthOfExpensesRelatingToLicenseOfPatent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="AmendmentMember" id="nrxp_AmendmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfFractionalSharesIssuedRelatedWithReserveStockSplit" id="nrxp_NumberOfFractionalSharesIssuedRelatedWithReserveStockSplit" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="NumberOfCommonStockReceivedInFractionalShares" id="nrxp_NumberOfCommonStockReceivedInFractionalShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="SecondAmendmentMember" id="nrxp_SecondAmendmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="StreetervilleNoteMember" id="nrxp_StreetervilleNoteMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AtmPurchaseAgreementMember" id="nrxp_AtmPurchaseAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="UnderwrittenPublicOfferingMember" id="nrxp_UnderwrittenPublicOfferingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FebruaryUnderwritingAgreementMember" id="nrxp_FebruaryUnderwritingAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfDaysOptionToPurchaseAdditionalShares" id="nrxp_NumberOfDaysOptionToPurchaseAdditionalShares" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="EfHuttonLlcMember" id="nrxp_EfHuttonLlcMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantExercisableTermFromDateOfIssuance" id="nrxp_WarrantExercisableTermFromDateOfIssuance" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="WarrantMaturityTermFromDateOfIssuance" id="nrxp_WarrantMaturityTermFromDateOfIssuance" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesIssuedUponExerciseOfOptionsGrantedPercentageToSharePool" id="nrxp_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesIssuedUponExerciseOfOptionsGrantedPercentageToSharePool" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantedInPeriodFairValue" id="nrxp_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantedInPeriodFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardIncreaseInNumberOfSharesAvailableForGrant" id="nrxp_ShareBasedCompensationArrangementByShareBasedPaymentAwardIncreaseInNumberOfSharesAvailableForGrant" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="February2024PublicOfferingMember" id="nrxp_February2024PublicOfferingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PercentageOfPremiumOfferingPrice" id="nrxp_PercentageOfPremiumOfferingPrice" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="February2024OverAllotmentOptionMember" id="nrxp_February2024OverAllotmentOptionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AlvogenLicensingAgreementMember" id="nrxp_AlvogenLicensingAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfOpenTaxAudits" id="nrxp_NumberOfOpenTaxAudits" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="AggregateProspectusSupplementAmount" id="nrxp_AggregateProspectusSupplementAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PercentageOfBeneficialOwnershipLimitationOfPostExercise" id="nrxp_PercentageOfBeneficialOwnershipLimitationOfPostExercise" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="PercentageBeneficialOwnershipLimitationMayBeWaivedUpToMaximum" id="nrxp_PercentageBeneficialOwnershipLimitationMayBeWaivedUpToMaximum" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightsIssued" id="nrxp_ClassOfWarrantOrRightsIssued" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="April2024UnderwrittenPublicOfferingMember" id="nrxp_April2024UnderwrittenPublicOfferingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OverAllotmentOptionPeriod" id="nrxp_OverAllotmentOptionPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PercentageOfSharesIssuableUponExerciseOfWarrants" id="nrxp_PercentageOfSharesIssuableUponExerciseOfWarrants" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="UnderwritersWarrantMember" id="nrxp_UnderwritersWarrantMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantsAndRightsOutstandingExercisableTerm" id="nrxp_WarrantsAndRightsOutstandingExercisableTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="WarrantsAndRightsOutstandingExpirationTerm" id="nrxp_WarrantsAndRightsOutstandingExpirationTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="FractionalStockIssuedDuringPeriodSharesReverseStockSplits" id="nrxp_FractionalStockIssuedDuringPeriodSharesReverseStockSplits" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AlvogenMilestoneAdvanceMember" id="nrxp_AlvogenMilestoneAdvanceMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="StreetervilleLlcMember" id="nrxp_StreetervilleLlcMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ProceedsReceivedInAprilMember" id="nrxp_ProceedsReceivedInAprilMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
</xsd:schema>
