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  <xsd:element id="nrxp_DebtInstrumentNumberOfTranches" name="DebtInstrumentNumberOfTranches" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant"/>
  <xsd:element id="nrxp_DebtInstrumentOriginalIssuanceDiscount" name="DebtInstrumentOriginalIssuanceDiscount" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="instant"/>
  <xsd:element id="nrxp_DebtIssuanceCosts" name="DebtIssuanceCosts" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_DocumentAndEntityInformation" name="DocumentAndEntityInformation" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_EndOfPhaseIClinicalTrialsOfLicensedProductMember" name="EndOfPhaseIClinicalTrialsOfLicensedProductMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_EndOfPhaseIIClinicalTrialsOfLicensedProductMember" name="EndOfPhaseIIClinicalTrialsOfLicensedProductMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_EndOfPhaseIIIClinicalTrialsOfLicensedProductMember" name="EndOfPhaseIIIClinicalTrialsOfLicensedProductMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_EquityOfferingMaximumOfferingAmount" name="EquityOfferingMaximumOfferingAmount" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant"/>
  <xsd:element abstract="true" id="nrxp_ExclusiveLicenseAgreementMember" name="ExclusiveLicenseAgreementMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_ExpectedSavings" name="ExpectedSavings" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant"/>
  <xsd:element id="nrxp_FairValueAdjustmentOfConvertibleDebt" name="FairValueAdjustmentOfConvertibleDebt" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityConversionToShares" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityConversionToShares" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityInitialRecognition" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityInitialRecognition" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_FebruaryOverallotmentOptionMember" name="FebruaryOverallotmentOptionMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_FebruaryUnderwriterWarrantsMember" name="FebruaryUnderwriterWarrantsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_FebruaryUnderwritingAgreementMember" name="FebruaryUnderwritingAgreementMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_FebruaryWarrantsMember" name="FebruaryWarrantsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_FirstCommercialSaleOfLicensedProductInEuropeMember" name="FirstCommercialSaleOfLicensedProductInEuropeMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_FirstCommercialSaleOfLicensedProductInUsMember" name="FirstCommercialSaleOfLicensedProductInUsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_GainLossOnConsiderationSharesAndWarrants" name="GainLossOnConsiderationSharesAndWarrants" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_GainLossOnConvertibleDebtRedemption" name="GainLossOnConvertibleDebtRedemption" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_GainLossOnIssuanceOfCommonStock" name="GainLossOnIssuanceOfCommonStock" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_GainLossOnIssuanceOfRegisteredDirectOffering" name="GainLossOnIssuanceOfRegisteredDirectOffering" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_GlytechLicenseAgreementMember" name="GlytechLicenseAgreementMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_HopeTherapeuticsIncMember" name="HopeTherapeuticsIncMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_IncreaseDecreaseInInsuranceLoanPayable" name="IncreaseDecreaseInInsuranceLoanPayable" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_LeaseContractualTermOfficeSpaceRentalMember" name="LeaseContractualTermOfficeSpaceRentalMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_LicenseAgreementCumulativePayments" name="LicenseAgreementCumulativePayments" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_LicenseAgreementMaintenanceFee" name="LicenseAgreementMaintenanceFee" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant"/>
  <xsd:element id="nrxp_LicenseAgreementMilestonePayment" name="LicenseAgreementMilestonePayment" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_LicenseAgreementsMilestonePaymentsConditionalReductionPercentage" name="LicenseAgreementsMilestonePaymentsConditionalReductionPercentage" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="instant"/>
  <xsd:element id="nrxp_LitigationSettlementPaymentInstallmentOne" name="LitigationSettlementPaymentInstallmentOne" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_LitigationSettlementPaymentInstallmentTwo" name="LitigationSettlementPaymentInstallmentTwo" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_LongtermDebtPrincipalOnly" name="LongtermDebtPrincipalOnly" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant"/>
  <xsd:element abstract="true" id="nrxp_MeasurementInputCostOfDebtMember" name="MeasurementInputCostOfDebtMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_MeasurementInputProbabilityOfDefaultMember" name="MeasurementInputProbabilityOfDefaultMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_NRXPharmaceuticalsIncMember" name="NRXPharmaceuticalsIncMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_NeuroRxMember" name="NeuroRxMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_NondesignatedPreferredStockMember" name="NondesignatedPreferredStockMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_NoteToFinancialStatementDetailsTextual" name="NoteToFinancialStatementDetailsTextual" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_NotesToFinancialStatements" name="NotesToFinancialStatements" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_NotesToFinancialStatementsAbstract" name="NotesToFinancialStatementsAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_Nrx100Member" name="Nrx100Member" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_PatentLicenseMember" name="PatentLicenseMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_PaymentForLicenseAgreementMaintenanceFee" name="PaymentForLicenseAgreementMaintenanceFee" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_PlacementAgentFeePercentOfGrossProceeds" name="PlacementAgentFeePercentOfGrossProceeds" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="instant"/>
  <xsd:element id="nrxp_PrepaidClinicalDevelopmentExpense" name="PrepaidClinicalDevelopmentExpense" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant"/>
  <xsd:element id="nrxp_PrepaidExpensesAndOtherCurrentAssetsTextBlock" name="PrepaidExpensesAndOtherCurrentAssetsTextBlock" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_PrivatePlacementPremiumPercentage" name="PrivatePlacementPremiumPercentage" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_PrivatePlacementWarrantsMember" name="PrivatePlacementWarrantsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_ProceedsFromInsuranceLoans" name="ProceedsFromInsuranceLoans" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_ProceedsFromIssuanceOfCommonStockAndWarrantsNet" name="ProceedsFromIssuanceOfCommonStockAndWarrantsNet" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_ProductsCoveredByLicensedPatentsMember" name="ProductsCoveredByLicensedPatentsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_ProductsCoveredByValidClaimsMember" name="ProductsCoveredByValidClaimsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_PublicWarrantsMember" name="PublicWarrantsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_RDPurchaseAgreementMember" name="RDPurchaseAgreementMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_RegisteredDirectOfferingMember" name="RegisteredDirectOfferingMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_RepaymentsOfInsuranceLoans" name="RepaymentsOfInsuranceLoans" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_RisksAndUncertaintiesPolicyTextBlock" name="RisksAndUncertaintiesPolicyTextBlock" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_RoyaltyPercentage" name="RoyaltyPercentage" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="instant"/>
  <xsd:element abstract="true" id="nrxp_SarahHerzogMemorialHospitalLicenseAgreementMember" name="SarahHerzogMemorialHospitalLicenseAgreementMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_ScheduleOfMilestonePaymentsTableTextBlock" name="ScheduleOfMilestonePaymentsTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_SeriesAConvertiblePreferredStockMember" name="SeriesAConvertiblePreferredStockMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_SharebasedCompensationArrangementBySharebasedPaymentAwardAnnualPercentageIncreaseInAuthorizedShares" name="SharebasedCompensationArrangementBySharebasedPaymentAwardAnnualPercentageIncreaseInAuthorizedShares" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="instant"/>
  <xsd:element id="nrxp_SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodGrantDateFairValue" name="SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodGrantDateFairValue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsGrantsInPeriodGrantDateFairValue" name="SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsGrantsInPeriodGrantDateFairValue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsGrantsInPeriodWeightedAverageRemainingContractualTerm" name="SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsGrantsInPeriodWeightedAverageRemainingContractualTerm" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_StockIssuanceToVendorMember" name="StockIssuanceToVendorMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_StockIssuedAsOfferingCosts" name="StockIssuedAsOfferingCosts" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_StockIssuedDuringPeriodSharesSharesIssuedFromRepricing" name="StockIssuedDuringPeriodSharesSharesIssuedFromRepricing" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_StockIssuedDuringPeriodValueSharesIssuedFromRepricing" name="StockIssuedDuringPeriodValueSharesIssuedFromRepricing" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_StockSubscriptionsReceivableWriteOff" name="StockSubscriptionsReceivableWriteOff" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_StreetervileComplaintMember" name="StreetervileComplaintMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_StreetervilleConvertibleNoteMember" name="StreetervilleConvertibleNoteMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_SubstituteWarrantsMember" name="SubstituteWarrantsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_The2016OmnibusIncentivePlanMember" name="The2016OmnibusIncentivePlanMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_The2021OmnibusIncentivePlanMember" name="The2021OmnibusIncentivePlanMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_ThirdTrancheNotesMember" name="ThirdTrancheNotesMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_ThirdTrancheNotesWarrantsMember" name="ThirdTrancheNotesWarrantsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_UnderwriterOverallotmentWarrantsMember" name="UnderwriterOverallotmentWarrantsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_UnrestrictedUponNewDrugApplicationDateMember" name="UnrestrictedUponNewDrugApplicationDateMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_UnrestrictedUponNewDrugApprovalDateMember" name="UnrestrictedUponNewDrugApprovalDateMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="nrxp_WarrantsIssuedDueToVwapAdjustments" name="WarrantsIssuedDueToVwapAdjustments" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_WarrantsIssuedForAlvogenAgreementAmendmentMember" name="WarrantsIssuedForAlvogenAgreementAmendmentMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_WarrantsMember" name="WarrantsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_WarrantsOtherThanConsiderationWarrantsMember" name="WarrantsOtherThanConsiderationWarrantsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-10-stockbased-compensation-schedule-of-restricted-stock-awards-details" name="statement-statement-note-10-stockbased-compensation-schedule-of-restricted-stock-awards-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-10-stockbased-compensation-schedule-of-stock-options-details" name="statement-statement-note-10-stockbased-compensation-schedule-of-stock-options-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-10-stockbased-compensation-schedule-of-stockbased-compensation-details" name="statement-statement-note-10-stockbased-compensation-schedule-of-stockbased-compensation-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-10-stockbased-compensation-tables" name="statement-statement-note-10-stockbased-compensation-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-11-fair-value-measurements-schedule-of-assets-and-liabilities-on-a-recurring-basis-details" name="statement-statement-note-11-fair-value-measurements-schedule-of-assets-and-liabilities-on-a-recurring-basis-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-11-fair-value-measurements-schedule-of-level-3-fair-value-changes-details" name="statement-statement-note-11-fair-value-measurements-schedule-of-level-3-fair-value-changes-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-11-fair-value-measurements-schedule-of-significant-inputs-details" name="statement-statement-note-11-fair-value-measurements-schedule-of-significant-inputs-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-11-fair-value-measurements-tables" name="statement-statement-note-11-fair-value-measurements-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-12-segment-reporting-longlived-assets-details" name="statement-statement-note-12-segment-reporting-longlived-assets-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-12-segment-reporting-reconciliation-of-loss-from-operations-to-total-loss-details" name="statement-statement-note-12-segment-reporting-reconciliation-of-loss-from-operations-to-total-loss-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-12-segment-reporting-tables" name="statement-statement-note-12-segment-reporting-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-3-summary-of-significant-accounting-policies-schedule-of-antidilutive-securities-details" name="statement-statement-note-3-summary-of-significant-accounting-policies-schedule-of-antidilutive-securities-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-3-summary-of-significant-accounting-policies-tables" name="statement-statement-note-3-summary-of-significant-accounting-policies-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-4-prepaid-expense-and-other-current-assets-schedule-of-prepaid-expense-and-other-current-assets-details" name="statement-statement-note-4-prepaid-expense-and-other-current-assets-schedule-of-prepaid-expense-and-other-current-assets-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-4-prepaid-expense-and-other-current-assets-tables" name="statement-statement-note-4-prepaid-expense-and-other-current-assets-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-5-accrued-and-other-current-liabilities-schedule-of-accrued-and-other-current-liabilities-details" name="statement-statement-note-5-accrued-and-other-current-liabilities-schedule-of-accrued-and-other-current-liabilities-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-5-accrued-and-other-current-liabilities-tables" name="statement-statement-note-5-accrued-and-other-current-liabilities-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-8-commitments-and-contingencies-schedule-of-milestone-payments-details" name="statement-statement-note-8-commitments-and-contingencies-schedule-of-milestone-payments-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-8-commitments-and-contingencies-tables" name="statement-statement-note-8-commitments-and-contingencies-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-9-equity-schedule-of-warrants-details" name="statement-statement-note-9-equity-schedule-of-warrants-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-note-9-equity-tables" name="statement-statement-note-9-equity-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="nrxp_statement-statement-significant-accounting-policies-policies" name="statement-statement-significant-accounting-policies-policies" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
</xsd:schema>
